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KMID : 0357919790130030311
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Korean Journal of Pathology
1979 Volume.13 No. 3 p.311 ~ p.315
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Clinico-Pathological Study on 4 Cases of Yolk Sac Tumor -Including 1 case combined with Drsgerminoma-
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서재홍(徐在烘)/J.H. Suh
박영진(朴永珍)/이명희(李明姬)/지정희(池貞熙)/Y.J. Park/M.H. Lee/J.H. Chi
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Abstract
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Yolk sac tumor is a rare malignant germ cell tumor that occurs in both gonadal and
extragonadal tissues.
Its germinal origin was first recognized by Teilum who suggested the term
"Endodermal sinus tumor" for this neoplasm.
The most specific feature of this rare neoplasm is the blood vessels and peripheral
sleeve of malignant embryonic epithelial cells with sinusoidal and papillary or
gloineruloid pattern.
We experienced 4 cases of yolk sac tumor, one of which is combined with
dysgerminoma of ovary in a 25-year old women, 2 cases arises in the sacrococcygium,
one case of testis in a 3-year old boy and one case occurred in the ovary in a 15-year
old women.
The demonstration of alpha-fetoprotein in the serum of patients were turned out as all
positive and positive alpha-fetoprotein with yolk sac tumor lentos further support to the
yolk sac origin of these tumors.
The 4 cases are reported with review of the literature.
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KEYWORD
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